{"id":98734,"date":"2023-08-31T16:18:16","date_gmt":"2023-08-31T08:18:16","guid":{"rendered":"https:\/\/techtalentsuk.com\/?post_type=jobpost&p=98734"},"modified":"2023-08-31T16:18:16","modified_gmt":"2023-08-31T08:18:16","slug":"2023083102","status":"publish","type":"jobpost","link":"https:\/\/techtalentsuk.com\/en\/jobs\/2023083102\/","title":{"rendered":"\u6d59\u6c5f\u5927\u5b66\u836f\u5b66\u9662\/\u533b\u5b66\u4e2d\u5fc3\u5e73\u6e0a\u8bfe\u9898\u7ec42023\u5e74\u8bda\u8058\u535a\u58eb\u540e\u7814\u7a76\u5458"},"content":{"rendered":"

\u6d59\u6c5f\u5927\u5b66\u5e73\u6e0a\u8bfe\u9898\u7ec4\uff0c\u8bda\u8058\u535a\u58eb\u540e\u7814\u7a76\u5458\uff0c\u4e3b\u8981\u7814\u7a76\u65b9\u5411\u5982\u4e0b\uff1a<\/span><\/p>\n

\uff08<\/span>1<\/span>\uff09<\/span>\u667a\u80fd\u5316\u57fa\u56e0\u7f16\u8f91\u9012\u9001\u7cfb\u7edf\u7684\u7814\u7a76<\/span><\/b>\uff1a\u672c\u8bfe\u9898\u7ec4\u524d\u671f\u5df2\u7ecf\u5f00\u53d1\u4e86\u9ad8\u6548\u7cbe\u51c6\u7684\u57fa\u56e0\u7f16\u8f91\u9012\u9001\u53ca\u8c03\u63a7\u7cfb\u7edf\uff0c\u5728\u6b64\u57fa\u7840\u4e0a\u5df2\u5728\u8fdb\u884c\u4e00\u7cfb\u5217\u76f8\u5173\u7814\u7a76\uff0c\u5e76\u5efa\u7acb\u4e86\u51e0\u79cd\u9ad8\u6548\u57fa\u56e0\u7f16\u8f91\u4f20\u9012\u7cfb\u7edf\u53ca\u7cbe\u51c6\u6fc0\u6d3b\u7684\u63a7\u5236\u7cfb\u7edf\uff0c\u7528\u4e8e\u75be\u75c5\u7684\u6cbb\u7597\u3002<\/span><\/p>\n

\uff08<\/span>2<\/span>\uff09<\/span>\u57fa\u56e0\u7f16\u8f91\u7684\u65b0\u578b\u836f\u7269\u5236\u5242\u7684\u5f00\u53d1<\/span><\/b>\uff1a\u8bfe\u9898\u7ec4\u76ee\u524d\u6b63\u5728\u8fdb\u884c\u57fa\u4e8e\u57fa\u56e0\u7f16\u8f91\u65b0\u5242\u578b\u7814\u7a76\uff08\u5305\u62ec\u6c14\u96fe\u5242\u53ca\u900f\u76ae\u5236\u5242\u7b49\uff09\uff0c\u7528\u4e8e\u5c40\u90e8\u57fa\u56e0\u6cbb\u7597\u3002<\/span><\/p>\n

\uff08<\/span>3<\/span>\uff09<\/span>\u5de5\u7a0b\u5316\u7ec6\u80de\u7684\u7814\u7a76\u4e0e\u5f00\u53d1<\/span><\/b>\uff1a\u76ee\u524d\u8bfe\u9898\u7ec4\u6b63\u5728\u7814\u7a76\u4ee5\u54fa\u4e73\u7ec6\u80de\u6216\u7ec6\u83cc\u4e3a\u57fa\u7840\u7684\u9012\u9001\u8f7d\u4f53\uff0c\u5e76\u5bf9\u7ec6\u83cc\u6216\u7ec6\u80de\u8fdb\u884c\u57fa\u56e0\u5de5\u7a0b\u5316\uff0c\u81f4\u529b\u4e8e\u7814\u7a76\u8111\u90e8\u53ca\u5176\u4ed6\u76f8\u5173\u75be\u75c5\u667a\u80fd\u7ed9\u836f\u53ca\u8c03\u63a7\uff0c\u5b9e\u73b0\u751f\u7269\u5927\u5206\u5b50\u7684\u7cbe\u51c6\u9012\u9001\u4e0e\u6cbb\u7597\u3002<\/span><\/p>\n

\u8bfe\u9898\u7ec4\u914d\u5907\u4e86\u5c0f\u52a8\u7269\u6210\u50cf\u4eea\u3001<\/span>Western Blotting<\/span>\u663e\u5f71\u4eea\u3001\u52a8\u6001\u5149\u6563\u5c04\u7eb3\u7c73\u7c92\u5ea6\u4eea\u3001\u5168\u81ea\u52a8\u51dd\u80f6\u6210\u50cf\u7cfb\u7edf\u3001\u8367\u5149\u5012\u7f6e\u663e\u5fae\u955c\u3001<\/span>PCR<\/span>\u4eea\u3001\u6052\u6e29\u6447\u5e8a\u3001\u81ea\u52a8\u9ad8\u538b\u706d\u83cc\u9505\u3001\u8d85\u4f4e\u6e29\u51b0\u7bb1\u3001\u9176\u6807\u4eea\u3001\u65cb\u8f6c\u84b8\u53d1\u4eea\u3001\u51b7\u51bb\u5e72\u71e5\u4eea\u3001\u8d85\u58f0\u7c89\u788e\u4eea\u3001\u6d01\u51c0\u5de5\u4f5c\u53f0\u53ca\u751f\u7269\u5b89\u5168\u67dc\u7b49\u5e38\u89c4\u4eea\u5668\u53ca\u8bbe\u5907\uff0c\u5e76\u914d\u5907\u4e86\u5316\u5b66\u5408\u6210\u5b9e\u9a8c\u5ba4\uff0c\u7ec6\u80de\u57f9\u517b\u95f4\u3001\u7ec6\u83cc\u64cd\u4f5c\u95f4\u53ca\u5c0f\u52a8\u7269\u5904\u7406\u95f4\uff0c\u57fa\u672c\u53ef\u6ee1\u8db3\u5b8c\u6210\u8bfe\u9898\u7684\u72ec\u7acb\u9700\u6c42\u3002\u6b64\u5916\uff0c\u6d59\u6c5f\u5927\u5b66\u836f\u5b66\u9662\u53ca\u6bd7\u90bb\u7684\u533b\u5b66\u9662\u3001\u751f\u547d\u79d1\u5b66\u9662\u3001\u751f\u547d\u7814\u7a76\u9662\u5177\u6709\u826f\u597d\u7684\u516c\u5171\u79d1\u7814\u5e73\u53f0\u53ca\u5927\u578b\u4eea\u5668\uff0c\u53ef\u4ee5\u4fdd\u8bc1\u79d1\u7814\u7684\u987a\u5229\u8fdb\u884c\u3002<\/span><\/p>\n

\u8bfe\u9898\u7ec4\u6210\u7acb\u4e8e<\/span>2018<\/span>\u5e74\u521d\uff0c\u76ee\u524d\u6709\u5316\u5b66\u5408\u6210\u3001\u9ad8\u5206\u5b50\u3001\u5206\u5b50\u751f\u7269\u5b66\u3001\u4e34\u5e8a\u533b\u5b66\u7b49\u4e0d\u540c\u80cc\u666f\u7684\u7855\u58eb\u751f\u3001\u535a\u58eb\u751f\u53ca\u535a\u58eb\u540e<\/span>10<\/span>\u4f59\u4eba\uff0c\u5df2\u719f\u7ec3\u638c\u63e1\u76f8\u5173\u7814\u7a76\u6240\u9700\u7684\u591a\u9879\u5173\u952e\u6280\u672f\uff0c\u5e76\u5f00\u53d1\u4e86\u591a\u79cd\u836f\u7269\u9012\u9001\u7cfb\u7edf\uff0c\u540c\u65f6\u4e5f\u4e0e\u56fd\u5185\u5916\u591a\u6240\u9ad8\u6821\u53ca\u7814\u7a76\u6240\u5c55\u5f00\u4e86\u5e7f\u6cdb\u5408\u4f5c\u3002\u672c\u8bfe\u9898\u7ec4\u59cb\u7ec8\u4ee5\u4eba\u4e3a\u672c\uff0c\u901a\u8fc7\u57f9\u517b\u79d1\u7814\u5174\u8da3\u548c\u80fd\u529b\uff0c\u5e76\u5728\u6d59\u6c5f\u5927\u5b66\u826f\u597d\u7684\u79d1\u7814\u6c1b\u56f4\u7684\u5f71\u54cd\u4e0b\uff0c\u63d0\u9ad8\u79d1\u7814\u7d20\u517b\u548c\u6c34\u5e73\uff0c\u662f\u6211\u4eec\u7684\u7528\u4eba\u7406\u5ff5\u3002\u8bfe\u9898\u7ec4\u6c14\u6c1b\u826f\u597d\uff0c\u7ecf\u8d39\u5145\u8db3\u3002<\/span><\/p>\n

\u76ee\u524d\u535a\u58eb\u540e\u85aa\u916c\u6309\u6d59\u6c5f\u5927\u5b66\u533b\u5b66\u4e2d\u5fc3\uff08\u4f59\u676d\uff09\u53ca\u6d59\u6c5f\u5927\u5b66\u76f8\u5173\u653f\u7b56\u6267\u884c\uff0c\u5177\u4f53\u85aa\u916c\u4e00\u4e8b\u4e00\u8bae\u3002\u535a\u58eb\u540e\u51fa\u7ad9\u540e\u5982\u7559\u676d\u5dde\u5de5\u4f5c\uff0c\u6309\u653f\u7b56\u4eab\u670940-60\u4e07\u5143\u7684\u751f\u6d3b\u8865\u52a9\u3002\u6b22\u8fce\u6765\u4fe1\u54a8\u8be2\u76f8\u5173\u60c5\u51b5\uff1aapplication@techtalentsuk.com\uff0c\u90ae\u4ef6\u6807<\/span>\u9898\u6ce8\u660e\uff1a<\/span>\u5e94\u8058\u5c97\u4f4d<\/span><\/b>+<\/span><\/b>\u6bd5\u4e1a\u5b66\u6821<\/span><\/b>+<\/span><\/b>\u672c\u4eba\u59d3\u540d\u3002<\/span><\/b><\/p>\n

\u5fae\u4fe1\uff1a<\/span>gzsgzju<\/span>\uff0c\u6211\u4eec\u70ed\u5ff1\u6b22\u8fce\u60a8\u7684\u52a0\u76df\u3002<\/span><\/p>\n

\u8bfe\u9898\u7ec4\u8d1f\u8d23\u4eba\u7b80\u4ecb<\/span><\/b><\/p>\n

\u5e73\u6e0a\uff0c\u6d59\u6c5f\u5927\u5b66\u957f\u8058\u6559\u6388\uff0c\u535a\u58eb\u751f\u5bfc\u5e08\uff0c\u6d59\u6c5f\u5927\u5b66\u836f\u5b66\u9662\u836f\u5b66\u7cfb\u526f\u4e3b\u4efb\uff0c\u4e2d\u56fd\u836f\u5b66\u4f1a\u836f\u5242\u4e13\u4e1a\u59d4\u5458\u4f1a\u9752\u5e74\u59d4\u5458\uff0c\u201c<\/span>QRJH<\/span>\u201d\u9752\u5e74\u9879\u76ee\u83b7\u5f97\u8005\u3002\u4e8e<\/span>2012<\/span>\u5e74\u83b7\u5f97\u65b0\u52a0\u5761\u56fd\u7acb\u5927\u5b66\u535a\u58eb\u5b66\u4f4d\uff0c\u4e4b\u540e\u5206\u522b\u5728\u65b0\u52a0\u5761\u79d1\u5b66\u6280\u672f\u5c40\u6750\u6599\u5de5\u7a0b\u7814\u7a76\u6240\u3001\u6fb3\u5927\u5229\u4e9a\u58a8\u5c14\u672c\u5927\u5b66\u53ca\u65b0\u52a0\u5761\u5357\u6d0b\u7406\u5de5\u5927\u5b66\u4ece\u4e8b\u79d1\u7814\u5de5\u4f5c\uff0c\u4e3b\u8981\u4ece\u4e8b\u9ad8\u5206\u5b50\u836f\u7269\u8f7d\u4f53\u7684\u8bbe\u8ba1\u4e0e\u5e94\u7528\u3002<\/span>2017<\/span>\u5e74\u8fdb\u5165\u4ee5\u201c\u767e\u4eba\u8ba1\u5212\u201d\u5f15\u8fdb\u6d59\u6c5f\u5927\u5b66\u836f\u5b66\u9662\u5de5\u4f5c\u81f3\u4eca\u3002\u76ee\u524d\u4e3a\u4e2d\u56fd\u836f\u5b66\u4f1a\u836f\u5242\u4e13\u4e1a\u59d4\u5458\u4f1a\u9752\u5e74\u59d4\u5458\u3001\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u7eb3\u7c73\u80bf\u7624\u5b66\u4e13\u4e1a\u59d4\u5458\u4f1a\u59d4\u5458\u3001\u300a<\/span>Advanced Drug Delivery Reviews<\/span>\u300b\u4e13\u520a\u4e3b\u7f16\uff08<\/span>168<\/span>\u671f\uff09\u3001\u300a<\/span>Chinese Chemical Letters<\/span>\u300b\u7f16\u59d4\u3001\u300a\u81ea\u7136\uff1a\u836f\u7269\u53d1\u73b0\u300b\u4e2d\u6587\u7248\u7f16\u59d4\u3001\u300a<\/span>Acta Pharmaceutica Sinica<\/span>\u300b\u53ca\u300a<\/span>Asian Journal of Pharmaceutical Sciences<\/span>\u300b\u9752\u5e74\u7f16\u59d4\u3002<\/span><\/p>\n

\u4e3b\u8981\u4ece\u4e8b\u751f\u7269\u5927\u5206\u5b50\u836f\u7269\u9012\u9001\u7cfb\u7edf\u7684\u8bbe\u8ba1\u4e0e\u75be\u75c5\u6cbb\u7597\uff0c\u8fc4\u4eca\u4e3a\u6b62\u5728\u56fd\u9645<\/span>SCI<\/span>\u520a\u7269\u4e0a\u5df2\u53d1\u8868\u8bba\u6587<\/span>60<\/span>\u4f59\u7bc7\uff0c\u5176\u4e2d\u72ec\u7acb\u5efa\u7ec4\u540e\uff0c\u4f5c\u4e3a\u901a\u8baf\u4f5c\u8005\u5728<\/span>PNAS, Science Advances, Advanced Materials<\/span>\u7b49\u56fd\u9645<\/span>SCI<\/span>\u520a\u7269\u4e0a\u53d1\u8868\u8bba\u6587<\/span>30<\/span>\u4f59\u7bc7\u3001\u6388\u6743\u53d1\u660e\u4e13\u5229<\/span>2<\/span>\u9879\u3002\u7814\u7a76\u9879\u76ee\u83b7\u5f97\u5305\u62ec\u56fd\u5bb6\u91cd\u70b9\u7814\u53d1\u8ba1\u5212\u3001\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u9762\u4e0a\u9879\u76ee\u3001\u53ca\u6d59\u6c5f\u7701\u6770\u51fa\u9752\u5e74\u9879\u76ee\u7b49\u8bfe\u9898\u652f\u6301\u3002\u76ee\u524d\u5df2\u57f9\u517b\u535a\u58eb\u540e<\/span>2<\/span>\u540d\uff0c\u535a\u58eb\u751f<\/span>3<\/span>\u540d\uff08\u5176\u4e2d<\/span>1<\/span>\u540d\u83b7\u201c\u535a\u65b0\u8ba1\u5212\u201d\u9879\u76ee\u652f\u6301\uff09\u3002\u73b0\u6307\u5bfc\u535a\u58eb\u540e<\/span>3<\/span>\u540d\uff08\u542b\u8054\u5408\u57f9\u517b<\/span>1<\/span>\u540d<\/span>, <\/span>\u5176\u4e2d<\/span>2<\/span>\u540d\u83b7\u5f97\u9752\u5e74\u57fa\u91d1\u53ca\u535a\u58eb\u540e\u9762\u4e0a\u57fa\u91d1\uff09\u3001\u535a\u58eb\u751f<\/span>8<\/span>\u540d\uff08\u542b\u8054\u5408\u57f9\u517b\uff09\uff0c\u7855\u58eb\u751f<\/span>3<\/span>\u540d\u3002<\/span><\/p>\n

\u8bfe\u9898\u7ec4\u5341\u7bc7\u4ee3\u8868\u6027\u8bba\u6587\uff08<\/span><\/b>*<\/span><\/b>\u901a\u8baf\u4f5c\u8005\uff09<\/span><\/b><\/p>\n

(1) <\/span>X. Xu, T. Tang, J. Guo, H. Xin, <\/span>Y. Ping<\/span><\/b>*. A Dual-Specific CRISPR-Cas Nanosystem for Precision Therapeutic Editing of Liver Disorders. <\/span>Signal Transduct. Target. Ther.<\/span><\/i> 2022<\/span><\/b>, In Press (IF=18.187)<\/span><\/p>\n

(2) <\/span>T. Wan, Q. Pan, C. Liu, J. Guo, B. Li, X. Yan, Y. Cheng*, <\/span>Y. Ping<\/span><\/b>*. A Duplex CRISPR-Cas9 Ribonucleoprotein Nanomedicine for Colorectal Cancer Gene Therapy. <\/span>Nano Lett. <\/span><\/i>2021<\/span><\/b>, <\/span>21<\/span><\/i>, 9761-9771. (IF=11.238)<\/span><\/p>\n

(3) <\/span>X. Yan, Q. Pan, H. Xin, Y. Chen, <\/span>Y. Ping<\/span><\/b>*. Genome-Editing Prodrug: Targeted Delivery and Conditional Stabilization of CRISPR\/Cas9 for Precision Therapy of Inflammatory Disease. <\/span>Sci. Adv.<\/span><\/i> 2021<\/span><\/b>, <\/span>7<\/span><\/i>, eabj0624. (IF=14.136)<\/span><\/p>\n

(4) <\/span>J. Guo, T. Wan, B. Li, Q. Pan, H. Xin, Y. Qiu, <\/span>Y. Ping<\/span><\/b>*. Rational Design of Poly(disulfide)s as a Universal Platform for Delivery of CRISPR\/Cas9 Machineries towards Therapeutic Genome Editing. <\/span>ACS Cent. Sci.<\/span><\/i> 2021<\/span><\/b>, <\/span>7<\/span><\/i>, 990-1000. (IF=14.553)<\/span><\/p>\n

(5) <\/span>T. Wan, P. Qi,<\/span> Y. Ping<\/span><\/b>*. Microneedle-Assisted Genome Editing: A Transdermal Strategy of Targeting <\/span>NLRP3 <\/span><\/i>by CRISPR\/Cas9 for Synergistic Therapy of Inflammatory Skin Disorders. <\/span>Sci. Adv.<\/span><\/i> 2021<\/span><\/b>, <\/span>7<\/span><\/i>, eabe2888. (IF=14.136)<\/span><\/p>\n

(6) <\/span>H. Tang, X. Xu,<\/span> Y. <\/span><\/b>Chen, H. Xin, T. Wan, B. Li, H. Pan, D. Li, <\/span>Y. Ping<\/span><\/b>*. Reprogramming Tumor Microenvironment through Second Near-Infrared Photothermal Genome Editing of PD-L1 mediated by Supramolecular Gold Nanorods for Enhanced Cancer Immunotherapy. <\/span>Adv. Mater.<\/span><\/i> 2021<\/span><\/b>, 2006003. (front cover, IF=30.849)<\/span><\/p>\n

(7) <\/span>X. Chen, Y. Chen, H. Xin, T. Wan, <\/span>Y. Ping<\/span><\/b>*. Near-Infrared Engineering of Photothermal NanoCRISPR for Programmable Genome Editing. <\/span>Proc. Natl. Acad. Sci. USA<\/span><\/i>, <\/span>2020<\/span><\/b>, <\/span>117<\/span><\/i>, 2395-2405. (IF=11.189)<\/span><\/p>\n

(8) <\/span>D. Wu<\/span>#<\/span>, X. Chen<\/span>#<\/span>, J. Zhou, Y. Chen, T. Wan, Y. Wang, A. Lin, Y. Ruan, Z. Chen, X. Song, W. Fang*, H. Duan*, <\/span>Y. Ping<\/span><\/b>*. <\/span>Mater. Horiz.<\/span><\/i> 2020<\/span><\/b>, <\/span>7<\/span><\/i>, 2929-2935. (back cover, IF=13.266)<\/span><\/p>\n

(9) <\/span>Q. Chen, M. Wu, G. Huang, G. Tang*, <\/span>Y. Ping<\/span><\/b>*. Bioengineering Bacterial Vesicle-Coated Polymeric Nanomedicine for Enhanced Cancer Immunotherapy and Metastasis Prevention. <\/span>Nano Lett.<\/span><\/i> 2020<\/span><\/b>, <\/span>20<\/span><\/i>, 11-21. (IF=11.238)<\/span><\/p>\n

(10) <\/span>C. Liu, T. Wan, H. Wang, S. Zhang, <\/span>Y. Ping<\/span><\/b>*, Y. Cheng* A boronic acid-rich dendrimer with robust and unprecedented efficiency for cytosolic protein delivery and CRISPR\/Cas9 gene editing. <\/span>Sci. Adv. <\/span><\/i>2019<\/span><\/b>, <\/span>5<\/span><\/i>, eaaw8922. (IF=14.136)<\/span><\/p>","protected":false},"excerpt":{"rendered":"

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